ea0024p3 | (1) | BSPED2010
Amin N L
, Barth J H
, Field H P
, Frazer S
, Finlay E
, Tyerman K
, Feather S
, Fitzpatrick M
, Saville G
, Alvi S
, Mushtaq T
Background: Type 1 pseudohypoaldosteronism (PHA) is characterised by resistance to aldosterone action, resulting in salt wasting, hyperkalaemia and metabolic acidosis in the neonatal period. Type 1 PHA can be classified as Renal PHA (autosomal dominant (AD)), and the more severe Multiple target organ defect / systemic PHA (autosomal recessive (AR)). The aim of this study was to ascertain the incidence of PHA, and characterise mode of presentation, management and clinical outco...